Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 15/20 | 0.55 |
| ▸ | CLK1 | P49759 | 12/20 | 0.55 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.50 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 5/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.41 |
| ▸ | AXL | P30530 | 5/20 | 0.41 |
| ▸ | FLT4 | P35916 | 5/20 | 0.41 |
| ▸ | FLT3 | P36888 | 5/20 | 0.41 |
| ▸ | CLK2 | P49760 | 5/20 | 0.41 |
| ▸ | MAP4K2 | Q12851 | 5/20 | 0.41 |
| ▸ | CAMK2B | Q13554 | 5/20 | 0.41 |
| ▸ | CAMK2G | Q13555 | 5/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 5/20 | 0.41 |
| ▸ | PTK6 | Q13882 | 5/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 5/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 5/20 | 0.41 |
| ▸ | MINK1 | Q8N4C8 | 5/20 | 0.41 |
| ▸ | PRKD2 | Q9BZL6 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30399459 | 1.00 | DYRK1A (0.55) | DYRK1ACLK1DYRK1BDYRK2PRKD3 | |
| SCHEMBL26177220 | 0.88 | DYRK1A (0.53) | DYRK1ACLK1DYRK1BDYRK2PRKD3 | |
| SCHEMBL30400318 | 0.88 | DYRK1A (0.53) | DYRK1ACLK1DYRK1BDYRK2PRKD3 | |
| SCHEMBL26177218 | 0.87 | DYRK1A (0.52) | DYRK1ACLK1DYRK1BDYRK2PRKD3 | |
| SCHEMBL30400687 | 0.87 | DYRK1A (0.52) | DYRK1ACLK1DYRK1BDYRK2PRKD3 | |
| SCHEMBL26176793 | 0.82 | KIT (0.44) | DYRK1ACLK1DYRK1BDYRK2AXL | |
| SCHEMBL26177219 | 0.81 | DYRK1A (0.55) | DYRK1ACLK1DYRK1BDYRK2PRKD3 | |
| SCHEMBL26177215 | 0.81 | DYRK1A (0.57) | DYRK1ACLK1DYRK1BDYRK2PRKD3 | |
| SCHEMBL30399726 | 0.80 | DYRK1A (0.51) | DYRK1ACLK1DYRK1BDYRK2PRKD3 | |
| SCHEMBL26175183 | 0.80 | DYRK1A (0.51) | DYRK1ACLK1DYRK1BDYRK2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192686-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AND PREPARATION AND USES THEREOF | TENARX, INC. | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192686-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | DYRK1A 1/4885CLK1 268/4885DYRK1B 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.