Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 19/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 15/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26185719 | 0.86 | CSNK1E (0.43) | CSNK1ECSNK1D | |
| SCHEMBL24277111 | 0.85 | CSNK1E (0.41) | CSNK1ECSNK1D | |
| SCHEMBL17373666 | 0.81 | CSNK1E (0.50) | CSNK1ECSNK1D | |
| SCHEMBL26185725 | 0.79 | CSNK1E (0.39) | CSNK1ECSNK1D | |
| SCHEMBL26185728 | 0.77 | GRM5 (0.52) | — | |
| SCHEMBL24553792 | 0.73 | CSNK1E (0.52) | CSNK1ECSNK1D | |
| SCHEMBL18171221 | 0.72 | CSNK1E (0.63) | CSNK1ECSNK1D | |
| SCHEMBL24277086 | 0.71 | CSNK1E (0.43) | CSNK1ECSNK1D | |
| SCHEMBL16722750 | 0.70 | CSNK1E (0.65) | CSNK1ECSNK1D | |
| SCHEMBL24553867 | 0.70 | GRM5 (0.51) | CSNK1ECSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331732-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331732-A1 | HETEROCYCLIC GLP-1 AGONISTS | GLP1R, GIPR, GCGR | CSNK1E 2813/4885CSNK1D 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.