Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 19/20 | 0.74 |
| ▸ | CSNK2B | P67870 | 18/20 | 0.74 |
| ▸ | CSNK2A2 | P19784 | 17/20 | 0.74 |
| ▸ | ABCG2 | Q9UNQ0 | 15/20 | 0.74 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL261265 | 0.85 | CSNK2A1 (1.00) | CSNK2A1CSNK2BCSNK2A2ABCG2CSNK2A3 | |
| SCHEMBL262740 | 0.85 | CSNK2A1 (1.00) | CSNK2A1CSNK2BCSNK2A2ABCG2CSNK2A3 | |
| SCHEMBL262572 | 0.76 | CSNK2B (0.71) | CSNK2A1CSNK2BCSNK2A2ABCG2CSNK2A3 | |
| SCHEMBL262515 | 0.76 | CSNK2A1 (0.67) | CSNK2A1CSNK2BCSNK2A2ABCG2CSNK2A3 | |
| SCHEMBL261280 | 0.75 | CSNK2B (1.00) | CSNK2A1CSNK2BCSNK2A2ABCG2CSNK2A3 | |
| SCHEMBL261139 | 0.72 | CSNK2B (1.00) | CSNK2A1CSNK2BCSNK2A2ABCG2CSNK2A3 | |
| SCHEMBL263301 | 0.72 | CSNK2B (0.73) | CSNK2A1CSNK2BCSNK2A2ABCG2CSNK2A3 | |
| SCHEMBL263638 | 0.70 | CSNK2B (0.74) | CSNK2A1CSNK2BCSNK2A2ABCG2CSNK2A3 | |
| SCHEMBL262461 | 0.70 | CSNK2B (0.70) | CSNK2A1CSNK2BCSNK2A2ABCG2CSNK2A3 | |
| SCHEMBL261530 | 0.70 | CSNK2B (1.00) | CSNK2A1CSNK2BCSNK2A2ABCG2CSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133913-B2 | Substituted indeno [1,2-b]indole derivatives as novel inhibitors of protein kinase CK2 and their use as tumor therapeutic agents, cytostatics and diagnostic aids | Heinrich-Heine Universitat Dusseldof (DE) | 2012-03-13 | — | — | US | disclosed |