⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912324 | 1.00 | — | — | |
| SCHEMBL12899686 | 1.00 | — | — | |
| SCHEMBL12899708 | 1.00 | — | — | |
| SCHEMBL12930305 | 1.00 | — | — | |
| SCHEMBL7603697 | 1.00 | — | — | |
| SCHEMBL264563 | 1.00 | — | — | |
| SCHEMBL9914024 | 0.89 | CHRM5 (0.48) | — | |
| SCHEMBL12791894 | 0.89 | CHRM5 (0.48) | — | |
| SCHEMBL20886791 | 0.89 | CHRM5 (0.48) | — | |
| SCHEMBL6931043 | 0.89 | CHRM5 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346893-B2 | Process for the preparation of highly O-sulfated, epimerized derivatives of K5 polysacchride and intermediates therein | GLYCORES 2000 S.R.L. (IT) | 2016-05-24 | — | — | US | disclosed |
| US-20140316129-A1 | PROCESS FOR THE PREPARATION OF HIGHLY O-SULFATED, EPIMERIZED DERIVATIVES OF K5 POLYSACCHRIDE AND INTERMEDIATES THEREIN | GLYCORES 2000 S.R.L. (IT) | 2014-10-23 | — | — | US | disclosed |
| US-8440812-B2 | Analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation | NOGRA PHARMA LIMITED (IE) | 2013-05-14 | — | — | US | disclosed |
| US-8440812-B2 | Analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation | NOGRA PHARMA LIMITED (IE) | 2013-05-14 | — | — | US | disclosed |
| US-20120253029-A1 | PROCESS FOR THE PREPARATION OF HIGHLY O-SULFATED EPIMERIZED DERIVATIVES OF K5 POLYSACCHARIDE AND INTERMEDIATES THEREIN | GLYCORES 2000 S.R.L. (IT) | 2012-10-04 | — | — | US | disclosed |
| US-20120094948-A1 | Analogous Compounds of 6-Thioguanosine Triphosphate, their use in Medical Fields and Processes for their Preparation | GIULIANI INTERNATIONAL LIMITED | 2012-04-19 | — | — | US | disclosed |
| US-20120094948-A1 | Analogous Compounds of 6-Thioguanosine Triphosphate, their use in Medical Fields and Processes for their Preparation | GIULIANI INTERNATIONAL LIMITED | 2012-04-19 | — | — | US | disclosed |
| US-8114986-B2 | Analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation | GIULIANI INTERNATIONAL LIMITED (IE) | 2012-02-14 | — | — | US | disclosed |
| US-8114986-B2 | Analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation | GIULIANI INTERNATIONAL LIMITED (IE) | 2012-02-14 | — | — | US | disclosed |
| US-20110021766-A1 | EPIMERIZED DERIVATIVES OF K5 POLYSACCHARIDE WITH A VERY HIGH DEGREE OF SULFATION | Glycores 2000 S.r.L (IT) | 2011-01-27 | — | — | US | disclosed |
| US-20100323980-A9 | Improvements to analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation | NOGRA PHARMA LIMITED (IE) | 2010-12-23 | — | — | US | disclosed |
| US-20100323980-A9 | Improvements to analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation | NOGRA PHARMA LIMITED (IE) | 2010-12-23 | — | — | US | disclosed |
| US-20090258837-A1 | Analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation | GIULIANI INTERNATIONAL LIMITED (IE) | 2009-10-15 | — | — | US | disclosed |
| US-20090258837-A1 | Analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation | GIULIANI INTERNATIONAL LIMITED (IE) | 2009-10-15 | — | — | US | disclosed |
| US-20090105185-A1 | Nucleosides with anti-hepatitis B Virus activity | SCHINAZI RAYMOND F | 2009-04-23 | — | — | US | disclosed |
| US-7468357-B2 | Nucleosides with anti-hepatitis B virus activity | EMORY UNIVERSITY (US) | 2008-12-23 | — | — | US | disclosed |