Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.54 |
| ▸ | DDB1 | Q16531 | 18/20 | 0.54 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.36 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30990811 | 1.00 | CRBN (0.54) | CRBNDDB1OXER1IKZF3 | |
| SCHEMBL30169156 | 1.00 | CRBN (0.54) | CRBNDDB1OXER1IKZF3 | |
| SCHEMBL30169198 | 1.00 | CRBN (0.54) | CRBNDDB1OXER1IKZF3 | |
| SCHEMBL22526201 | 1.00 | CRBN (0.54) | CRBNDDB1OXER1IKZF3 | |
| SCHEMBL22526770 | 1.00 | CRBN (0.54) | CRBNDDB1OXER1IKZF3 | |
| SCHEMBL25123384 | 1.00 | CRBN (0.54) | CRBNDDB1OXER1IKZF3 | |
| SCHEMBL30169288 | 1.00 | CRBN (0.54) | CRBNDDB1OXER1IKZF3 | |
| SCHEMBL30990646 | 1.00 | CRBN (0.54) | CRBNDDB1OXER1IKZF3 | |
| SCHEMBL22526772 | 1.00 | CRBN (0.54) | CRBNDDB1OXER1IKZF3 | |
| SCHEMBL22526735 | 0.99 | CRBN (0.55) | CRBNDDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | STAT4, STAT1, STAT3 | CRBN 171/4885DDB1 3993/4885OXER1 3763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.