Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.33 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GSDMD | P57764 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119578 | 0.97 | EHMT2 (0.35) | EHMT2EHMT1ABCB11HTTGSDMD | |
| Hydrochloric Acid SCHEMBL27913333 | 0.94 | EHMT2 (0.33) | EHMT2EHMT1ABCB11HTTGSDMD | |
| Iodide SCHEMBL7033668 | 0.94 | EHMT2 (0.33) | EHMT2EHMT1ABCB11HTTGSDMD | |
| Hydrochloric Acid SCHEMBL261161 | 0.94 | EHMT2 (0.33) | EHMT2EHMT1ABCB11HTTGSDMD | |
| Fluoride Ion SCHEMBL4607229 | 0.94 | EHMT2 (0.33) | EHMT2EHMT1ABCB11HTTGSDMD | |
| SCHEMBL7032131 | 0.87 | — | — | |
| SCHEMBL7035110 | 0.85 | TSHR (0.39) | LMNAALDH1A1TSHR | |
| SCHEMBL8717245 | 0.85 | CA12 (0.37) | CA12CA1CA2CA9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL25405995 | 0.83 | CA12 (0.36) | CA12CA1CA2CA9TSHR | |
| Acetic Acid SCHEMBL261148 | 0.83 | CA1 (0.36) | CA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 332 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621178-A | Preparation process of fluoroethylene carbonate | 内蒙古源宏精细化工有限公司 | 2022-06-14 | — | — | CN | claimed |
| EP-2292627-B1 | Aqueous catalytic process for the preparation of thiocarboxylate silane | MOMENTIVE PERFORMANCE MAT INC (US) | 2016-03-30 | — | — | EP | claimed |
| EP-1869057-B1 | AQUEOUS CATALYTIC PROCESS FOR THE PREPARATION OF THIOCARBOXYLATE SILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2012-12-19 | — | — | EP | claimed |
| US-8013173-B2 | Method of purifying dianhydrides, the dianhydrides formed thereby, and polyetherimides formed therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-09-06 | — | — | US | claimed |
| EP-1960408-B1 | PROCESS FOR THE PRODUCTION OF MERCAPTOALKYLALKOXYSILANES | MOMENTIVE PERFORMANCE MAT INC (US) | 2011-07-20 | — | — | EP | claimed |
| EP-2292627-A1 | Aqueous catalytic process for the preparation of thiocarboxylate silane | Momentive Performance Materials Inc. (US) | 2011-03-09 | — | — | EP | claimed |
| EP-2280963-A1 | METHOD OF PURIFYING DIANHYDRIDES, THE DIANHYDRIDES FORMED THEREBY, AND POLYETHERIMIDES FORMED THEREFROM | SABIC Innovative Plastics IP B.V. (NL) | 2011-02-09 | — | — | EP | claimed |
| EP-2271611-A1 | METHODS FOR PREPARING OXYDIPHTHALIC ANHYDRIDES | SABIC Innovative Plastics IP B.V. (NL) | 2011-01-12 | — | — | EP | claimed |
| WO-2009120215-A9 | METHODS FOR PREPARING OXYDIPHTHALIC ANHYDRIDES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-11-11 | — | — | WO | claimed |
| US-7674920-B2 | Methods for preparing oxydiphthalic anhydrides, oxydiphthalic anhydrides prepared thereby, and polyetherimides derived therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-03-09 | — | — | US | claimed |
| US-5898080-A | Method for preparing diaryl carbonates employing hexaalkylguanidinium halides | GENERAL ELECTRIC COMPANY (US) | 1999-04-27 | — | — | US | claimed |
| US-5807965-A | Interfacial copolyestercarbonate method using catalyst comprising hexaalkylguanidinium salt and tertiary amine | GENERAL ELECTRIC COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5760272-A | REACTING A HYDROXYAROMATIC COMPOUND WITH OXYGEN AND CARBON MONOXIDE IN PRESENCE OF A CATALYST MIXTURE | GENERAL ELECTRIC COMPANY (US) | 1998-06-02 | — | — | US | claimed |
| EP-0816414-A2 | Preparation of polyether polymers | GENERAL ELECTRIC COMPANY (US) | 1998-01-07 | — | — | EP | claimed |
| US-5663275-A | POLYETHERIMIDES, HIGH MOLECULAR WEIGHT, ENGINEERING RESINS | GENERAL ELECTRIC COMPANY (US) | 1997-09-02 | — | — | US | claimed |
| US-5438114-A | Heating with a primary amine in the presence of a non-metal containing catalyst of tertiary amine, tertiary phosphine, quaternary ammonium salt, quaternary phosphonium salt or hexaalkylguanidium salt or heterocyclic analog thereof | GENERAL ELECTRIC COMPANY (US) | 1995-08-01 | — | — | US | claimed |
| EP-0642544-A1 | PHASE TRANSFER CATALYZED PREPARATION OF AROMATIC POLYETHER POLYMERS | GENERAL ELECTRIC COMPANY (US) | 1995-03-15 | — | — | EP | claimed |
| WO-1994022939-A1 | PHASE TRANSFER CATALYZED PREPARATION OF AROMATIC POLYETHER POLYMERS | GENERAL ELECTRIC COMPANY (US) | 1994-10-13 | — | — | WO | claimed |
| US-5229482-A | Phase transfer catalyzed preparation of aromatic polyether polymers | GENERAL ELECTRIC COMPANY (US) | 1993-07-20 | — | — | US | claimed |
| US-5132423-A | Nucleophilic substitution reaction of alkali hydroxy- or mercaptoaromatic compound and heterocyclic substituted imide | GENERAL ELECTRIC COMPANY (US) | 1992-07-21 | — | — | US | claimed |