SCHEMBL262113

SCHEMBL262113

CCCCCCCCn1c2ccccc2c2cc([N+](=O)[O-])ccc21

nearest known ligand 0.71

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.71
MEN1 O00255 3/20 0.71
KMT2A Q03164 3/20 0.71
LMNA P02545 1/20 0.71
POLB P06746 1/20 0.68
ATM Q13315 1/20 0.68
SIGMAR1 Q99720 1/20 0.62
CNR2 P34972 11/20 0.56
CNR1 P21554 2/20 0.52
ACHE P22303 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5012036 1.00 MAPT (0.71) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL18261960 1.00 MAPT (0.71) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL1149826 0.99 MAPT (0.73) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL11413547 0.95 MAPT (0.75) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL3039635 0.93 MAPT (0.59) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL9397206 0.89 MAPT (0.79) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL18261959 0.86 MAPT (0.52) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL8179196 0.84 MAPT (0.71) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL149167 0.84 MAPT (1.00) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL29666347 0.84 MAPT (1.00) MAPTMEN1KMT2ALMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240085670-A1 METHODS OF MAKING A LOW-COST MINIATURE ACCOMMODATING OPTICAL IMAGING SYSTEM NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-03-14 US claimed
US-20240085670-A1 METHODS OF MAKING A LOW-COST MINIATURE ACCOMMODATING OPTICAL IMAGING SYSTEM NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-03-14 US disclosed
EP-2128132-B1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME ADEKA CORP (JP) 2014-01-15 EP disclosed
US-8133656-B2 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORPORATION (JP) 2012-03-13 US disclosed
US-20100075254-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME ADEKA CORPORATION (JP) 2010-03-25 US disclosed
EP-2128132-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR COMPRISING THE COMPOUND Adeka Corporation (JP) 2009-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100075254-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME CYP4A11, OXER1, NR2E3 MAPT 4252/4885MEN1 4584/4885KMT2A 3265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.