SCHEMBL26213697

SCHEMBL26213697

CCC(O)c1cc2cc(F)ccc2n1S(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 8/20 0.51
LMNA P02545 2/20 0.46
PPARG P37231 3/20 0.43
PPARD Q03181 1/20 0.43
NOD2 Q9HC29 2/20 0.43
NOD1 Q9Y239 2/20 0.43
PTGDR Q13258 4/20 0.42
PPARA Q07869 1/20 0.41
HTR6 P50406 1/20 0.40
KDM4E B2RXH2 1/20 0.39
TSHR P16473 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH3A1 P30838 1/20 0.38
ACLY P53396 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30270460 1.00 PTGDR2 (0.51) PTGDR2LMNAPPARGPPARDNOD2
SCHEMBL30270458 0.91 PTGDR2 (0.49) PTGDR2LMNAPPARGPPARDNOD2
SCHEMBL26213705 0.91 PTGDR2 (0.49) PTGDR2LMNAPPARGPPARDNOD2
SCHEMBL26213706 0.90 PTGDR2 (0.48) PTGDR2LMNAPPARGPPARDNOD2
SCHEMBL31058814 0.90 PTGDR2 (0.48) PTGDR2LMNAPPARGPPARDNOD2
SCHEMBL30270502 0.89 PTGDR2 (0.49) PTGDR2LMNAPPARGPPARDNOD2
SCHEMBL30270498 0.88 PTGDR2 (0.48) PTGDR2LMNAPPARGPPARDNOD2
SCHEMBL30270472 0.85 PTGDR2 (0.49) PTGDR2LMNAPPARGPPARDNOD2
SCHEMBL30270441 0.84 PTGDR2 (0.47) PTGDR2LMNAPPARGPPARDNOD2
SCHEMBL27178977 0.84 PTGDR2 (0.50) PTGDR2LMNAPPARGPPARDNOD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115843271-A Indole derivatives and their use for the treatment of cancer 克洛德贝纳尔-里昂第一大学 2023-03-24 CN disclosed