SCHEMBL26214

SCHEMBL26214

Clc1ccccc1C(Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.59
TSHR P16473 7/20 0.52
KCNA3 P22001 2/20 0.44
CYP19A1 P11511 4/20 0.43
CYP3A4 P08684 3/20 0.43
HTR2A P28223 2/20 0.43
HTR2C P28335 2/20 0.43
OPRK1 P41145 2/20 0.43
KCNH2 Q12809 2/20 0.43
LMNA P02545 2/20 0.43
CYP1A2 P05177 2/20 0.43
MAPK1 P28482 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ADRA1A P35348 1/20 0.43
MEN1 O00255 1/20 0.43
SLC22A1 O15245 1/20 0.43
NR1I2 O75469 1/20 0.43
GMNN O75496 1/20 0.43
USP2 O75604 1/20 0.43
TRPM2 O94759 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3239466 1.00 KCNN4 (0.59) KCNN4TSHRKCNA3CYP19A1CYP3A4
SCHEMBL29354141 1.00 KCNN4 (0.59) KCNN4TSHRKCNA3CYP19A1CYP3A4
Chlorotriphenylmethane SCHEMBL27733223 0.98 KCNN4 (0.57) KCNN4TSHRKCNA3CYP19A1CYP3A4
Hydrochloric Acid SCHEMBL29532967 0.98 KCNN4 (0.57) KCNN4TSHRKCNA3CYP19A1CYP3A4
Hydrazine SCHEMBL26109949 0.96 KCNN4 (0.61) KCNN4TSHRKCNA3CYP19A1CYP3A4
SCHEMBL11654993 0.95 KCNN4 (0.59) KCNN4TSHRKCNA3CYP19A1CYP3A4
Toluene SCHEMBL28713609 0.90 KCNN4 (0.50) KCNN4TSHRKCNA3CYP19A1CYP3A4
SCHEMBL23790036 0.88 KCNN4 (0.48) KCNN4TSHRKCNA3CYP19A1CYP3A4
SCHEMBL15087403 0.88 KCNN4 (0.48) KCNN4TSHRKCNA3CYP19A1CYP3A4
SCHEMBL13521990 0.88 KCNN4 (0.48) KCNN4TSHRKCNA3CYP19A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10699 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289851-A1 CYCLIC PEPTIDES FOR DELIVERING THERAPEUTICS ENTRADA THERAPEUTICS, INC. 2025-09-18 US claimed
CN-119350469-B Method for synthesizing CAGRILINTIDE by large fragment SPPS-LPPS mixing method 杭州诺澳生物医药科技有限公司 2025-05-23 CN claimed
WO-2025088147-A1 THERANOSTIC PSMA-TARGETING LIGANDS FOR THE DIAGNOSIS AND TREATMENT OF PSMA-EXPRESSING CANCERS AND THEIR SOLID PHASE SYNTHESIS Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2025-05-01 WO claimed
CN-119591674-A Cyclohexapeptide and preparation method and application thereof 陕西未来多肽生物科技有限公司 2025-03-11 CN claimed
CN-119529033-A Ultra-long-acting polypeptide for NPR-B targeting and application thereof in skeletal system diseases 中山大学 2025-02-28 CN claimed
CN-118994321-B Preparation method and application of cosmetic cyclic peptide reagent 杭州皓阳生物技术有限公司 2025-02-14 CN claimed
EP-4051691-B1 DOLASTATIN 10 ANALOG ARIEL SCIENT INNOVATIONS LTD (IL) 2025-02-12 EP claimed
CN-119350469-A Method for synthesizing CAGRILINTIDE by large fragment SPPS-LPPS mixing method 杭州诺澳生物医药科技有限公司 2025-01-24 CN claimed
CN-118994321-A Preparation method and application of cosmetic cyclic peptide reagent 杭州皓阳生物技术有限公司 2024-11-22 CN claimed
CN-118994172-A Preparation method of poncirtinib phosphate 广州科锐特生物科技有限公司 2024-11-22 CN claimed
WO-2002062804-A1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA S.P.A. (IT) 2002-08-15 WO claimed
WO-2001085758-A2 METHOD FOR PRODUCING POLYMER-BONDED 2-CHLOROTRITYL CHLORIDE LONZA AG (CH) 2001-11-15 WO claimed
WO-2001068598-A2 DOSING FORM FOR A POLYMER SUPPORT, USE OF SAID DOSING FORM IN ORGANIC CHEMICAL SYNTHESIS AND METHOD FOR PRODUCTION OF SAID DOSING FORM H. LUNDBECK A/S (DK) 2001-09-20 WO claimed
EP-0937097-B1 COMPOSITIONS AND METHODS FOR IMMOBILIZING NUCLEIC ACIDS TO SOLID SUPPORTS SEQUENOM INC (US) 2001-08-16 EP claimed
JP-2001501967-A 2001-02-13 JP claimed
US-6133436-A INCREASED SURFACE AREA FOR IMMOBILIZATION OF NUCLEIC ACIDS; FOR USE IN HYBRIDIZATIONS SEQUENOM, INC. (US) 2000-10-17 US claimed
EP-0937097-A1 COMPOSITIONS AND METHODS FOR IMMOBILIZING NUCLEIC ACIDS TO SOLID SUPPORTS SEQUENOM, INC. (US) 1999-08-25 EP claimed
WO-1998020019-A1 COMPOSITIONS AND METHODS FOR IMMOBILIZING NUCLEIC ACIDS TO SOLID SUPPORTS SEQUENOM, INC. (US) 1998-05-14 WO claimed
EP-0399430-B1 Process for preparation of crystal-line oxytitanium phthalocyanine MITSUBISHI CHEM IND (JP) 1994-10-26 EP claimed
US-5091540-A Process for preparing clotrimazole ERREGIERRE INDUSTRIA CHIMICA S.P.A. (IT) 1992-02-25 US claimed