Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 3/20 | 0.83 |
| ▸ | BTK | Q06187 | 6/20 | 0.78 |
| ▸ | HCK | P08631 | 4/20 | 0.78 |
| ▸ | NR2C2 | P49116 | 4/20 | 0.78 |
| ▸ | GCK | P35557 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | CSF1R | P07333 | 5/20 | 0.60 |
| ▸ | KIT | P10721 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | UBE2N | P61088 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 2/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29496427 | 0.89 | EPHA2 (1.00) | EPHA2BTKHCKNR2C2GCK | |
| SCHEMBL29435037 | 0.89 | EPHA2 (1.00) | EPHA2BTKHCKNR2C2GCK | |
| SCHEMBL20136698 | 0.89 | EPHA2 (1.00) | EPHA2BTKHCKNR2C2GCK | |
| SCHEMBL16810246 | 0.87 | BTK (1.00) | EPHA2BTKHCKNR2C2GCK | |
| SCHEMBL16810247 | 0.87 | EPHA2 (1.00) | EPHA2BTKHCKNR2C2GCK | |
| SCHEMBL18170278 | 0.86 | BTK (0.88) | EPHA2BTKHCKNR2C2GCK | |
| SCHEMBL26214307 | 0.86 | EPHA2 (0.84) | EPHA2BTKHCKNR2C2GCK | |
| SCHEMBL20355914 | 0.85 | EPHA2 (0.95) | EPHA2BTKHCKNR2C2GCK | |
| SCHEMBL26215027 | 0.80 | EPHA2 (0.72) | EPHA2BTKHCKNR2C2GCK | |
| SCHEMBL16810170 | 0.79 | BTK (1.00) | EPHA2BTKHCKNR2C2GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168107-A2 | COMPOUNDS AND COMPOSITIONS FOR ANITMALARIAL THERAPEUTIC AND PROPHYLACTIC USE | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-09-07 | — | — | WO | disclosed |