SCHEMBL26214942

SCHEMBL26214942

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nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.35
NR1I2 O75469 1/20 0.35
LMNA P02545 1/20 0.35
PGR P06401 1/20 0.35
PTPN1 P18031 1/20 0.34
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
RECQL P46063 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14554113 0.80 PTGS1 (0.39) PTGS1NR1I2LMNAPGRTSHR
SCHEMBL27264547 0.77 PTGS1 (0.39) PTGS1NR1I2LMNAPGRTSHR
SCHEMBL15834121 0.75
SCHEMBL13947488 0.75
SCHEMBL20686459 0.75
SCHEMBL17779212 0.71 TSHR (0.34) PTGS1NR1I2LMNAPGRPTPN1
SCHEMBL20739643 0.71
SCHEMBL14143136 0.71
SCHEMBL18951879 0.71
SCHEMBL19186039 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4242202-A1 BENZIMIDAZOLE DERIVATIVE AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) 2023-09-13 EP disclosed