Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26216135 | 0.95 | CYP4F2 (0.45) | TAAR1ALDH1A1NOTUMLMNAHPGD | |
| SCHEMBL26216133 | 0.91 | TAAR1 (0.47) | TAAR1ALDH1A1NOTUMLMNAHPGD | |
| SCHEMBL26216137 | 0.84 | CYP4F2 (0.44) | CYP4F2CYP4A11CYSLTR2CYSLTR1 | |
| SCHEMBL22418800 | 0.83 | TAAR1 (0.50) | TAAR1ALDH1A1NOTUMHPGDCTBP2 | |
| SCHEMBL3673001 | 0.81 | HDAC3 (0.57) | TAAR1ALDH1A1HPGDCTBP2PTGER1 | |
| SCHEMBL6722068 | 0.81 | TAAR1 (0.48) | TAAR1ALDH1A1NOTUMHPGDCTBP2 | |
| SCHEMBL8573889 | 0.81 | TAAR1 (0.53) | TAAR1ALDH1A1NOTUMHPGDCTBP2 | |
| SCHEMBL9863168 | 0.80 | HDAC3 (0.55) | TAAR1ALDH1A1HPGDCTBP2PTGER1 | |
| SCHEMBL29053313 | 0.80 | TAAR1 (0.47) | TAAR1ALDH1A1NOTUMHPGDCTBP2 | |
| SCHEMBL9863165 | 0.80 | HDAC3 (0.55) | TAAR1ALDH1A1HPGDCTBP2PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154756-A2 | THIONOLACTONES AS ADDITIVES FOR VINYL NETWORK DEGRADATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-08-17 | — | — | WO | disclosed |