Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729205 | 0.78 | TDP1 (0.45) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL25402997 | 0.77 | MEN1 (0.51) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL12482641 | 0.76 | TDP1 (0.56) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL25963695 | 0.75 | TDP1 (0.45) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL18938501 | 0.75 | TDP1 (0.49) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL13055395 | 0.74 | TDP1 (0.55) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL1979026 | 0.74 | TDP1 (0.55) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL24215258 | 0.74 | MEN1 (0.42) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL7154749 | 0.74 | MEN1 (0.42) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL3792861 | 0.73 | TDP1 (0.50) | MEN1GAAKMT2ATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443485-B1 | BIOMEDICAL DEVICES | BAUSCH & LOMB (US) | 2017-11-08 | — | — | EP | disclosed |
| EP-2443482-B1 | BIOMEDICAL DEVICES, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING THE SAME. | BAUSCH & LOMB (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-2443486-B1 | BIOMEDICAL DEVICES | BAUSCH & LOMB (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-2443483-B1 | MULTI-ARMED MACROMONOMERS, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING SAME. | BAUSCH & LOMB (US) | 2016-03-23 | — | — | EP | disclosed |
| US-9285508-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2016-03-15 | — | — | US | disclosed |
| EP-2443483-A1 | MULTI-ARMED MACROMONOMERS, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING SAME | Bausch & Lomb Incorporated (US) | 2012-04-25 | — | — | EP | disclosed |
| EP-2443486-A2 | BIOMEDICAL DEVICES | Bausch & Lomb Incorporated (US) | 2012-04-25 | — | — | EP | disclosed |
| US-8133960-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2012-03-13 | — | — | US | disclosed |
| US-8083348-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2011-12-27 | — | — | US | disclosed |
| WO-2010147875-A2 | BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010147865-A1 | MULTI-ARMED MACROMONOMERS, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING SAME | BAUSCH & LOMB INCORPORATED (US) | 2010-12-23 | — | — | WO | disclosed |
| US-20100317816-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100318185-A1 | Biomedical Devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100317817-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |