Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 4/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19111008 | 1.00 | DPP4 (0.48) | DPP4HTR1AHTR7ACEREN | |
| SCHEMBL26724818 | 0.86 | ACE (0.47) | ACEREN | |
| SCHEMBL17378268 | 0.86 | ACE (0.47) | ACEREN | |
| SCHEMBL871820 | 0.86 | ACE (0.61) | ACEREN | |
| SCHEMBL12863842 | 0.84 | SMN1; SMN2 (0.47) | DPP4HTR1AHTR7ACEREN | |
| SCHEMBL14463150 | 0.82 | DPP4 (0.51) | DPP4HTR1AHTR7ACE | |
| SCHEMBL10884099 | 0.80 | DPP4 (0.54) | DPP4HTR1AHTR7ACE | |
| SCHEMBL13954202 | 0.80 | DPP4 (0.51) | DPP4HTR1AHTR7ACE | |
| SCHEMBL29540069 | 0.79 | DPP4 (0.53) | DPP4HTR1AHTR7ACE | |
| SCHEMBL683068 | 0.79 | DPP4 (0.50) | DPP4HTR1AHTR7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | STAT4, STAT1, STAT3 | DPP4 189/4885HTR1A 3834/4885HTR7 2921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.