SCHEMBL26227197

SCHEMBL26227197

Cc1cc(C)c(-c2ccc3c(c2)c2c4c5cc6ccccc6cc5n5c6ccc(-c7c(C)cc(C)cc7C)cc6c(c6c7cc8ccccc8cc7n3c26)c45)c(C)c1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.40
CYP1A2 P05177 2/20 0.40
IKBKB O14920 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
MAPK9 P45984 1/20 0.32
MAPK14 Q16539 1/20 0.32
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
RAPGEF4 Q8WZA2 1/20 0.31
DRD2 P14416 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30
PSMB5 P28074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24601313 0.88 CYP1A2 (0.33) CYP2A6CYP1A2MAPTDRD2ALDH1A1
SCHEMBL21717857 0.88 CYP2A6 (0.42) CYP2A6CYP1A2IKBKBTDP1MAPK9
SCHEMBL24601459 0.87 CYP1A2 (0.40) CYP2A6CYP1A2MAPTDRD2ALDH1A1
SCHEMBL24601310 0.85 CYP1A2 (0.30) CYP2A6CYP1A2
SCHEMBL19563792 0.84 CYP1A2 (0.43) CYP2A6CYP1A2IKBKBTDP1MAPT
SCHEMBL24601615 0.83 CYP1A2 (0.39) CYP2A6CYP1A2MAPK9MAPK14MAPT
SCHEMBL26227213 0.83 CYP1A2 (0.41) CYP2A6CYP1A2TDP1MAPK9MAPK14
SCHEMBL21717383 0.83 CYP1A2 (0.44) CYP2A6CYP1A2TDP1MAPTHTT
SCHEMBL21717368 0.82 CYP2A6 (0.42) CYP2A6CYP1A2TDP1MAPTHTT
SCHEMBL24601307 0.81 CYP1A2 (0.32) CYP2A6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230292539-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230292539-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed