SCHEMBL26227476

SCHEMBL26227476

c1ccc(-c2ccccc2Nc2ccc(C3(c4ccccc4)c4ccccc4-c4ccccc43)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.46
▸ KMT2A Q03164 4/20 0.46
▸ MAPT P10636 4/20 0.46
▸ KDM4E B2RXH2 3/20 0.46
▸ LMNA P02545 3/20 0.46
▸ OPRK1 P41145 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ POLB P06746 1/20 0.46
▸ FABP3 P05413 1/20 0.41
▸ FABP4 P15090 1/20 0.41
▸ FABP5 Q01469 1/20 0.41
▸ AURKA O14965 1/20 0.40
▸ MAPK13 O15264 1/20 0.38
▸ MAPK12 P53778 1/20 0.38
▸ MAPK11 Q15759 1/20 0.38
▸ MAPK14 Q16539 1/20 0.38
▸ ESR1 P03372 1/20 0.36
▸ ESR2 Q92731 1/20 0.36
▸ PDK2 Q15119 1/20 0.35
▸ GAA P10253 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24883319 0.94 MEN1 (0.46) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL22662319 0.90 MEN1 (0.42) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL30353956 0.90 PDK2 (0.42) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL16926140 0.90 PDK2 (0.42) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL18212129 0.87 PDK2 (0.40) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL27385432 0.87 MEN1 (0.41) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL24882969 0.87 MEN1 (0.39) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL20871515 0.87 MEN1 (0.39) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL22920945 0.87 MEN1 (0.39) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL22920820 0.86 MEN1 (0.39) MEN1KMT2AMAPTKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230284470-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT COMPOUND DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-09-07 — — US disclosed
US-20230284470-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT COMPOUND DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-09-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230284470-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT COMPOUND OR10J3, ICOSLG, L1CAM MEN1 3680/4885KMT2A 1725/4885MAPT 1652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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