Gluconic Acid

Gluconic Acid

SCHEMBL262276

O=C(O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.[Na+].[OH-]

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A

The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.91
LMNA P02545 2/20 0.68
USP2 O75604 1/20 0.56
SLCO1B1 Q9Y6L6 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.52
TDP1 Q9NUW8 1/20 0.50
TSHR P16473 2/20 0.48
CYP2C9 P11712 1/20 0.48
OR51E2 Q9H255 1/20 0.40
KDM4E B2RXH2 2/20 0.38
PGD P52209 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gluconic Acid SCHEMBL28120184 1.00 PDE4A (0.91) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL27472789 0.95 PDE4A (0.91) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL27672177 0.95 PDE4A (0.91) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL28705777 0.95 PDE4A (0.91) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL16592174 0.95 PDE4A (1.00) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL15339348 0.95 PDE4A (1.00) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL13056936 0.95 PDE4A (1.00) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL19257183 0.95 PDE4A (1.00) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL21778048 0.95 PDE4A (1.00) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL16609838 0.95 PDE4A (1.00) PDE4ALMNAUSP2SLCO1B1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1464 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114246953-B Anti-cMet antibody drug conjugates and methods of use thereof 艾伯维生物制药股份有限公司 2024-07-09 CN claimed
EP-3837273-A1 IMPROVED PROTEIN RECOVERY Bristol-Myers Squibb Company (US) 2021-06-23 EP claimed
US-20210171573-A1 IMPROVED PROTEIN RECOVERY BRISTOL-MYERS SQUIBB COMPANY 2021-06-10 US claimed
WO-2020036903-A1 IMPROVED PROTEIN RECOVERY BRISTOL-MYERS SQUIBB COMPANY (US) 2020-02-20 WO claimed
EP-4519316-A1 NEW FORMULATION OF ANTI VISTA ANTIBODY PIERRE FABRE MEDICAMENT (FR) 2025-03-12 EP disclosed
US-12043663-B2 Anti-TNF-alpha-antibodies and functional fragments thereof TILLOTTS PHARMA AG (CH) 2024-07-23 US disclosed
WO-2024151978-A1 IL12 RECEPTOR AGONISTS AND METHODS OF USE THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2024-07-18 WO disclosed
WO-2024152014-A1 FGFR3 BINDING MOLECULES AND METHODS OF USE THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2024-07-18 WO disclosed
EP-3456738-B1 ANTIBODY VARIANTS TILLOTTS PHARMA AG (CH) 2024-07-17 EP disclosed
CN-118355031-A Anti-saccharide-LAMP 1 antibodies and uses thereof GO医疗股份有限公司 2024-07-16 CN disclosed
CN-118354789-A Anti-glyco-cMET antibodies and uses thereof GO医疗股份有限公司 2024-07-16 CN disclosed
EP-4396232-A1 ANTI-GLYCO-LAMP1 ANTIBODIES AND THEIR USES Go Therapeutics, Inc. (US) 2024-07-10 EP disclosed
WO-1989007945-A1 HUMAN RELAXIN FORMULATION GENENTECH, INC. (US) 1989-09-08 WO disclosed
WO-1989004177-A1 GAMMA INTERFERON FORMULATION GENENTECH, INC. (US) 1989-05-18 WO disclosed
EP-0284249-A1 Lyophilized lymphokine composition INTERFERON SCIENCES, INC. (US) 1988-09-28 EP disclosed
US-4675184-A VIRICIDES 501 Sunstar Kabushiki Kaisha (JP) 1987-06-23 US disclosed
EP-0080879-B1 PHARMACEUTICAL COMPOSITION CONTAINING INTERFERON IN STABLE STATE SUNSTAR KABUSHIKI KAISHA (JP) 1986-10-01 EP disclosed
US-4605555-A INTERFERON, POLYHYDRIC SUGAR ALCOHOL, ORGANIC ACID BUFFER SUN STAR KABUSHIKI KAISHA (JP) 1986-08-12 US disclosed
US-4605556-A APPLYING INTERFERON, POLYHYDRIC SUGAR ALCOHOL, AND ORGANIC ACID BUFFER SUN STAR KABUSHIKI KAISHA (JP) 1986-08-12 US disclosed
EP-0080879-A2 Pharmaceutical composition containing interferon in stable state SUNSTAR KABUSHIKI KAISHA (JP) 1983-06-08 EP disclosed