Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.53 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 2/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30890232 | 0.89 | DDB1 (0.54) | DDB1CRBNTNK2GPR119CCNC | |
| SCHEMBL22549536 | 0.88 | DDB1 (0.53) | DDB1CRBNTNK2GPR119CCNC | |
| SCHEMBL22549537 | 0.86 | DDB1 (0.52) | DDB1CRBNTNK2GPR119CCNC | |
| SCHEMBL520714 | 0.84 | DDB1 (0.56) | DDB1CRBNTNK2GPR119CCNC | |
| SCHEMBL3768448 | 0.83 | DDB1 (0.49) | DDB1CRBNGPR119CCNCCDK8 | |
| SCHEMBL12121174 | 0.83 | DDB1 (0.57) | DDB1CRBNTNK2GPR119CCNC | |
| SCHEMBL16096491 | 0.83 | DDB1 (0.57) | DDB1CRBNTNK2GPR119CCNC | |
| SCHEMBL1427617 | 0.81 | DDB1 (0.56) | DDB1CRBNTNK2GPR119CCNC | |
| SCHEMBL29249379 | 0.81 | DDB1 (0.56) | DDB1CRBNTNK2GPR119CCNC | |
| SCHEMBL12968055 | 0.81 | DDB1 (0.56) | DDB1CRBNTNK2GPR119CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111902141-A | Glucocerebroside binders for IKAROS degradation | C4医药公司 | 2020-11-06 | — | — | CN | disclosed |