⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2111051 | 0.97 | BACE1 (0.31) | — | |
| SCHEMBL8018914 | 0.97 | BACE1 (0.31) | — | |
| SCHEMBL2109619 | 0.97 | BACE1 (0.31) | — | |
| SCHEMBL2107187 | 0.94 | BACE1 (0.31) | — | |
| SCHEMBL2622940 | 0.89 | BACE1 (0.32) | — | |
| SCHEMBL2107983 | 0.86 | BACE1 (0.34) | — | |
| SCHEMBL2107982 | 0.86 | BACE1 (0.34) | — | |
| SCHEMBL2109588 | 0.86 | BACE1 (0.32) | — | |
| SCHEMBL8030834 | 0.86 | BACE1 (0.34) | — | |
| SCHEMBL16433342 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946210-B2 | Fused aminodihydrothiazine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-02-03 | — | — | US | disclosed |
| US-8946210-B2 | Fused aminodihydrothiazine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-02-03 | — | — | US | disclosed |
| US-20120094984-A1 | FUSED AMINODIHYDROTHIAZINE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| US-20120094984-A1 | FUSED AMINODIHYDROTHIAZINE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-04-19 | — | — | US | disclosed |