Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26230857 | 0.94 | ABL1 (0.50) | ABL1RIN1KMT2AMEN1POLB | |
| SCHEMBL26230900 | 0.94 | ABL1 (0.50) | ABL1RIN1KMT2AMEN1POLB | |
| SCHEMBL27727547 | 0.89 | ABL1 (0.49) | ABL1RIN1KMT2AMEN1POLB | |
| SCHEMBL27057456 | 0.86 | KMT2A (0.50) | ABL1RIN1KMT2AMEN1POLB | |
| SCHEMBL27056601 | 0.83 | KMT2A (0.47) | ABL1RIN1KMT2AMEN1POLB | |
| SCHEMBL27056608 | 0.83 | KMT2A (0.47) | ABL1RIN1KMT2AMEN1POLB | |
| SCHEMBL9195212 | 0.83 | KMT2A (0.47) | ABL1RIN1KMT2AMEN1POLB | |
| SCHEMBL22672647 | 0.82 | MEN1 (0.54) | ABL1RIN1KMT2AMEN1POLB | |
| SCHEMBL452423 | 0.82 | KMT2A (0.54) | ABL1RIN1KMT2AMEN1POLB | |
| SCHEMBL6055222 | 0.80 | ABL1 (0.52) | ABL1RIN1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230287418-A1 | MODIFIED SIRNA WITH REDUCED OFF-TARGET ACTIVITY | TUOJIE BIOTECH(SHANGHAI) CO., LTD. (CN) | 2023-09-14 | — | — | US | disclosed |