⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183284 | 1.00 | — | — | |
| SCHEMBL263466 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL27632266 | 0.97 | TSHR (0.45) | — | |
| SCHEMBL1085851 | 0.81 | — | — | |
| SCHEMBL503261 | 0.81 | — | — | |
| SCHEMBL1576713 | 0.81 | — | — | |
| SCHEMBL6281308 | 0.79 | — | — | |
| SCHEMBL28113756 | 0.77 | TSHR (0.47) | — | |
| SCHEMBL6912857 | 0.74 | — | — | |
| SCHEMBL18832123 | 0.74 | TSHR (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534240-B1 | YEAST MICROORGANISMS WITH REDUCED BY-PRODUCT ACCUMULATION FOR IMPROVED PRODUCTION OF FUELS, CHEMICALS, AND AMINO ACIDS | GEVO INC (US) | 2019-06-05 | — | — | EP | disclosed |
| US-9506074-B2 | Yeast microorganisms with reduced by-product accumulation for improved production of fuels, chemicals, and amino acids | GEVO, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-9012189-B2 | Modified alcohol dehydrogenases for the production of fuels and chemicals | GEVO, INC. (US) | 2015-04-21 | — | — | US | disclosed |
| US-20140212953-A1 | YEAST MICROORGANISMS WITH REDUCED BY-PRODUCT ACCUMULATION FOR IMPROVED PRODUCTION OF FUELS, CHEMICALS, AND AMINO ACIDS | GEVO, INC. (US) | 2014-07-31 | — | — | US | disclosed |
| US-20140017748-A1 | MODIFIED ALCOHOL DEHYDROGENASES FOR THE PRODUCTION OF FUELS AND CHEMICALS | GEVO, INC. (US) | 2014-01-16 | — | — | US | disclosed |
| EP-2534240-A2 | YEAST MICROORGANISMS WITH REDUCED BY-PRODUCT ACCUMULATION FOR IMPROVED PRODUCTION OF FUELS, CHEMICALS, AND AMINO ACIDS | GEVO, Inc. (US) | 2012-12-19 | — | — | EP | disclosed |
| US-8158404-B2 | Reduced by-product accumulation for improved production of isobutanol | GEVO, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-8153415-B2 | Reduced by-product accumulation for improved production of isobutanol | GEVO, INC. (US) | 2012-04-10 | — | — | US | disclosed |
| US-8133715-B2 | Reduced by-product accumulation for improved production of isobutanol | GEVO, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| WO-2011142865-A2 | YEAST MICROORGANISMS WITH REDUCED BY-PRODUCT ACCUMULATION FOR IMPROVED PRODUCTION OF FUELS, CHEMICALS, AND AMINO ACIDS | GEVO, INC. (US) | 2011-11-17 | — | — | WO | disclosed |
| US-20110275129-A1 | Reduced by-product accumulation for improved production of isobutanol | GEVO, INC. (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110236942-A1 | Reduced by-product accumulation for improved production of isobutanol | GEVO, INC. (US) | 2011-09-29 | — | — | US | disclosed |
| US-20110201090-A1 | Yeast microorganisms with reduced by-product accumulation for improved production of fuels, chemicals, and amino acids | GEVO, INC. (US) | 2011-08-18 | — | — | US | disclosed |
| US-20110201072-A1 | Modified alcohol dehydrogenases for the production of fuels and chemicals | GEVO, INC. (US) | 2011-08-18 | — | — | US | disclosed |
| US-20110201073-A1 | Reduced by-product accumulation for improved production of isobutanol | GEVO, INC. (US) | 2011-08-18 | — | — | US | disclosed |