SCHEMBL26233540

SCHEMBL26233540

CCC1O[C@@H](n2cnc3c(Cl)ncnc32)CC1O

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 1/20 0.60
▸ PNP P00491 1/20 0.51
▸ LMNA P02545 1/20 0.51
▸ TP53 P04637 1/20 0.51
▸ HTT P42858 1/20 0.51
▸ PDE4D Q08499 1/20 0.51
▸ PDE3A Q14432 1/20 0.51
▸ SMN1; SMN2 Q16637 1/20 0.51
▸ RXFP1 Q9HBX9 1/20 0.51
▸ POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14286676 1.00 HIF1A (0.60) HIF1APNPLMNATP53HTT
SCHEMBL9142309 0.89 HIF1A (0.71) HIF1APNPLMNATP53HTT
SCHEMBL21563936 0.89 HIF1A (0.71) HIF1APNPLMNATP53HTT
SCHEMBL30818467 0.89 HIF1A (0.71) HIF1APNPLMNATP53HTT
SCHEMBL5982644 0.89 HIF1A (0.71) HIF1APNPLMNATP53HTT
SCHEMBL5982637 0.89 HIF1A (0.71) HIF1APNPLMNATP53HTT
SCHEMBL18486197 0.89 HIF1A (0.71) HIF1APNPLMNATP53HTT
SCHEMBL21563846 0.89 HIF1A (0.71) HIF1APNPLMNATP53HTT
SCHEMBL18862687 0.89 HIF1A (0.71) HIF1APNPLMNATP53HTT
SCHEMBL14639883 0.86 POLB (0.62) HIF1APNPLMNATP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230264164-A1 HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY TRILINK BIOTECHNOLOGIES, LLC 2023-08-24 — — US disclosed
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