⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22446409 | 0.78 | — | — | |
| SCHEMBL21970953 | 0.77 | — | — | |
| SCHEMBL21970412 | 0.73 | — | — | |
| SCHEMBL23717566 | 0.71 | — | — | |
| SCHEMBL24689888 | 0.71 | — | — | |
| SCHEMBL1147801 | 0.67 | — | — | |
| SCHEMBL2272137 | 0.67 | — | — | |
| SCHEMBL8049997 | 0.67 | — | — | |
| SCHEMBL8049996 | 0.67 | — | — | |
| SCHEMBL25001242 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278989-A1 | ISOINDOLINONE INHIBITORS OF THE MDM2-P53 INTERACTION AND PROCESS FOR MAKING THEM | ASTEX THERAPEUTICS LIMITED (GB) | 2023-09-07 | — | — | US | disclosed |