Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 20/20 | 0.59 |
| ▸ | RAF1 | P04049 | 16/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29843095 | 0.87 | MAP2K1 (0.76) | MAP2K1RAF1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL960507 | 0.87 | MAP2K1 (0.76) | MAP2K1RAF1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25144214 | 0.86 | MAP2K1 (0.68) | MAP2K1RAF1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31190231 | 0.86 | MAP2K1 (0.67) | MAP2K1RAF1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25394234 | 0.86 | MAP2K1 (0.67) | MAP2K1RAF1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25144243 | 0.84 | MAP2K1 (0.65) | MAP2K1RAF1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25392026 | 0.81 | MAP2K1 (0.57) | MAP2K1RAF1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31190223 | 0.81 | MAP2K1 (0.57) | MAP2K1RAF1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25143990 | 0.80 | MAP2K1 (0.70) | MAP2K1RAF1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL26237957 | 0.79 | MAP2K1 (0.60) | MAP2K1RAF1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133472-A1 | MEK IMMUNE ONCOLOGY INHIBITORS AND THERAPEUTIC USES THEREOF | IMMUNEERING CORPORATION (US) | 2023-07-13 | — | — | WO | disclosed |