⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729983 | 0.77 | — | — | |
| SCHEMBL17662357 | 0.74 | — | — | |
| SCHEMBL2608294 | 0.74 | — | — | |
| SCHEMBL13787915 | 0.74 | — | — | |
| SCHEMBL1287173 | 0.72 | — | — | |
| SCHEMBL17239129 | 0.72 | — | — | |
| SCHEMBL9191921 | 0.72 | — | — | |
| SCHEMBL14958848 | 0.72 | CDK1 (0.30) | — | |
| SCHEMBL10283581 | 0.72 | — | — | |
| SCHEMBL17369690 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399322-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-12-14 | — | — | US | disclosed |
| US-11753403-B2 | EIF4E inhibitors and uses thereof | PIC Therapeutics, Inc. (US) | 2023-09-12 | — | — | US | disclosed |