Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | CCR8 | P51685 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509452 | 0.81 | KDM4E (0.55) | KDM4ENPC1LMNACCR1CCR5 | |
| SCHEMBL31038273 | 0.79 | KDM4E (0.53) | KDM4ENPC1LMNACCR1CCR5 | |
| SCHEMBL18818720 | 0.74 | KDM4E (0.55) | KDM4ENPC1LMNACCR1CCR5 | |
| SCHEMBL19961977 | 0.73 | KDM4E (0.55) | KDM4ENPC1LMNACCR1CCR5 | |
| SCHEMBL31199032 | 0.73 | KDM4E (0.55) | KDM4ENPC1LMNACCR1CCR5 | |
| SCHEMBL17532978 | 0.72 | KDM4E (0.65) | KDM4ENPC1LMNACCR1CCR5 | |
| SCHEMBL12902948 | 0.72 | KDM4E (0.65) | KDM4ENPC1LMNACCR1CCR5 | |
| SCHEMBL13525257 | 0.72 | KDM4E (0.58) | KDM4ENPC1LMNACCR1CCR5 | |
| SCHEMBL26242505 | 0.71 | MAOB (0.44) | KDM4ENPC1POLBSMN1; SMN2RAB9A | |
| Dipyridyl SCHEMBL4150988 | 0.71 | KDM4E (0.93) | KDM4ENPC1LMNACCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150201-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |