SCHEMBL2624844

SCHEMBL2624844

CC(C)=CCC/C(C)=C/CCC1(C)Oc2c(c(O)cc3c2CN(C(C(=O)O)c2ccccc2O)C3=O)CC1O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 8/20 0.34
APP P05067 2/20 0.34
PTPN1 P18031 1/20 0.34
NR1H4 Q96RI1 2/20 0.33
BACE1 P56817 1/20 0.33
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2624878 0.93 KDM4E (0.36) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL2624876 0.93 KDM4E (0.36) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL29725738 0.93 KDM4E (0.36) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL29403638 0.93 KDM4E (0.36) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL2624831 0.93 KDM4E (0.36) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL2624854 0.93 KDM4E (0.36) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL2624845 0.90 ABCG2 (0.35) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL2624842 0.90 ABCG2 (0.35) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL2624821 0.90 ABCG2 (0.35) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL2624850 0.90 ABCG2 (0.35) ALOX5APPPTPN1NR1H4BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8883462-B2 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) 2014-11-11 US disclosed
US-8883462-B2 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) 2014-11-11 US disclosed
US-20120100579-A1 TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER TOKYO UNIVERSITY OF AGRICLATURE AND TECHNOLOGY TLO CO., LTD. (JP) 2012-04-26 US disclosed
US-20120100579-A1 TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER TOKYO UNIVERSITY OF AGRICLATURE AND TECHNOLOGY TLO CO., LTD. (JP) 2012-04-26 US disclosed
US-8110596-B2 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) 2012-02-07 US disclosed
US-8110596-B2 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) 2012-02-07 US disclosed
US-20090216028-A1 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) 2009-08-27 US disclosed
US-20090216028-A1 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) 2009-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090216028-A1 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer PLAT, F2R, F12 ALOX5 833/4885APP 1517/4885PTPN1 2463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.