Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19650554 | 0.89 | BTK (0.58) | BTKCTSKGAAHSD11B1CYP2C9 | |
| SCHEMBL30073691 | 0.85 | BTK (0.50) | BTKCTSKGAAHSD11B1CYP2C9 | |
| SCHEMBL26361659 | 0.85 | BTK (0.50) | BTKCTSKGAAHSD11B1CYP2C9 | |
| SCHEMBL21918515 | 0.85 | BTK (0.50) | BTKCTSKGAAHSD11B1CYP2C9 | |
| SCHEMBL30399408 | 0.85 | BTK (0.50) | BTKCTSKGAAHSD11B1CYP2C9 | |
| SCHEMBL15318147 | 0.85 | BTK (0.57) | BTKCTSKGAAHSD11B1CYP2C9 | |
| SCHEMBL1707598 | 0.84 | BTK (0.56) | BTKCTSKGAAHSD11B1CYP2C9 | |
| SCHEMBL131490 | 0.84 | BTK (0.56) | BTKCTSKGAAHSD11B1CYP2C9 | |
| SCHEMBL17398093 | 0.84 | BTK (0.56) | BTKCTSKGAAHSD11B1CYP2C9 | |
| SCHEMBL12030066 | 0.84 | BTK (0.56) | BTKCTSKGAAHSD11B1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209485-A1 | COMPOUND HAVING ANTITUMOR ACTIVITY AND USE THEREOF | Innovstone Therapeutics Limited (CN) | 2023-07-12 | — | — | EP | disclosed |