Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.59 |
| ▸ | PTGDR | Q13258 | 7/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.59 |
| ▸ | PTGFR | P43088 | 1/20 | 0.59 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.59 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.36 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24103474 | 0.94 | PTGER4 (0.60) | PTGER4PTGDRTBXA2RPTGER1PTGFR | |
| SCHEMBL24104126 | 0.87 | PTGER4 (0.44) | PTGER4PTGDRTBXA2RPTGER1PTGFR | |
| SCHEMBL24103730 | 0.84 | PTGER4 (0.51) | PTGER4PTGDRTBXA2RPTGER1PTGFR | |
| SCHEMBL22414223 | 0.83 | PTGER4 (0.46) | PTGER4PTGDRTBXA2RPTGER1PTGFR | |
| SCHEMBL24104225 | 0.83 | PTGER4 (0.46) | PTGER4PTGDRTBXA2RPTGER1PTGFR | |
| SCHEMBL26255184 | 0.83 | PTGER4 (0.52) | PTGER4PTGDRTBXA2RPTGER1PTGFR | |
| SCHEMBL26432724 | 0.82 | PTGER4 (0.61) | PTGER4PTGDRTBXA2RPTGER1PTGFR | |
| SCHEMBL30498013 | 0.81 | PTGER4 (0.64) | PTGER4PTGDRTBXA2RPTGER1PTGFR | |
| SCHEMBL20541688 | 0.81 | PTGER4 (0.64) | PTGER4PTGDRTBXA2RPTGER1PTGFR | |
| SCHEMBL24104209 | 0.81 | PTGER4 (0.44) | PTGER4PTGDRTBXA2RPTGER1PTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11738009-B2 | Bicyclic compounds and their use in the treatment of cancer | TEMPEST THERAPEUTICS, INC. (US) | 2023-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11738009-B2 | Bicyclic compounds and their use in the treatment of cancer | PTGER4, PTGER1, PTGER3 | PTGER4 1/4885PTGDR 5/4885TBXA2R 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.