Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21625943 | 0.84 | HRH4 (0.31) | — | |
| SCHEMBL9965490 | 0.83 | MCL1 (0.39) | MCL1 | |
| SCHEMBL13645770 | 0.82 | CYP3A4 (0.30) | — | |
| SCHEMBL12952510 | 0.82 | EPHX1 (0.42) | — | |
| SCHEMBL13670700 | 0.77 | — | — | |
| SCHEMBL19080498 | 0.77 | — | — | |
| SCHEMBL11477580 | 0.77 | — | — | |
| SCHEMBL14773217 | 0.77 | — | — | |
| SCHEMBL14584358 | 0.75 | — | — | |
| SCHEMBL9197345 | 0.73 | MCL1 (0.33) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163763-B2 | Pyrimidine compounds, compositions and methods of use | GENENTECH, INC. (US) | 2012-04-24 | — | — | US | disclosed |