Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.58 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27436033 | 0.94 | GLP1R (0.62) | GLP1RLPAR3LPAR1NOD1SIRT2 | |
| SCHEMBL18202629 | 0.94 | GLP1R (0.62) | GLP1RLPAR3LPAR1NOD1SIRT2 | |
| SCHEMBL23475913 | 0.94 | GLP1R (0.62) | GLP1RLPAR3LPAR1NOD1SIRT2 | |
| SCHEMBL23475930 | 0.94 | GLP1R (0.62) | GLP1RLPAR3LPAR1NOD1SIRT2 | |
| SCHEMBL16853273 | 0.92 | GLP1R (0.64) | GLP1RLPAR3LPAR1NOD1SIRT2 | |
| SCHEMBL26255822 | 0.92 | GLP1R (0.64) | GLP1RLPAR3LPAR1NOD1SIRT2 | |
| SCHEMBL26257845 | 0.86 | GLP1R (0.64) | GLP1RLPAR3LPAR1NOD1SIRT2 | |
| SCHEMBL27436089 | 0.84 | GLP1R (0.50) | GLP1RSIRT2TLR2SIRT6SIRT1 | |
| SCHEMBL26257827 | 0.83 | GLP1R (0.67) | GLP1RLPAR3LPAR1NOD1SIRT2 | |
| SCHEMBL23567475 | 0.83 | GLP1R (0.69) | GLP1RNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212180-A1 | MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF | The Scripps Research Institute (US) | 2023-07-19 | — | — | EP | disclosed |