Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 17/20 | 0.67 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708561 | 0.80 | NAMPT (1.00) | NAMPT | |
| SCHEMBL14361080 | 0.80 | NAMPT (0.60) | NAMPT | |
| SCHEMBL3703772 | 0.80 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3705406 | 0.80 | NAMPT (1.00) | NAMPT | |
| SCHEMBL24815812 | 0.79 | NAMPT (0.73) | NAMPT | |
| SCHEMBL29986834 | 0.79 | NAMPT (0.73) | NAMPT | |
| SCHEMBL7602212 | 0.79 | NOTUM (0.61) | NAMPTNOTUMTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3700835 | 0.77 | NAMPT (0.71) | NAMPT | |
| SCHEMBL3696947 | 0.77 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3703446 | 0.77 | NAMPT (0.81) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856735-B1 | FUSED BICYCLIC HETEROCYCLES AS THERAPEUTIC AGENTS | UNIV NEW YORK (US) | 2023-09-06 | — | — | EP | disclosed |