SCHEMBL26257565

SCHEMBL26257565

CCCCNc1nc(N)c2[nH]c(=O)n(Cc3cccc(CCl)c3)c2n1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18563919 0.92 TLR7 (0.74) TLR7
SCHEMBL18584159 0.92 TLR7 (0.84) TLR7
SCHEMBL24007616 0.90 TLR7 (0.84) TLR7
SCHEMBL1146189 0.87 TLR7 (0.81) TLR7
SCHEMBL18563911 0.87 TLR7 (0.86) TLR7
SCHEMBL5459709 0.86 TLR7 (0.75) TLR7
SCHEMBL18584158 0.85 TLR7 (0.83) TLR7
SCHEMBL24233599 0.84 TLR7 (0.79) TLR7
SCHEMBL1146404 0.83 TLR7 (0.82) TLR7
SCHEMBL1146536 0.82 TLR7 (0.83) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702476-B2 Anti-EGFR combinations for treating tumors BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2023-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11702476-B2 Anti-EGFR combinations for treating tumors EGFR, ERBB3, ERBB2 TLR7 2007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.