Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 16/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22157408 | 1.00 | KCNH2 (0.54) | KCNH2DNM1PLA2G1BPLA2G2A | |
| SCHEMBL22157506 | 0.98 | KCNH2 (0.51) | KCNH2DNM1PLA2G1BPLA2G2A | |
| SCHEMBL27961138 | 0.91 | KCNH2 (0.45) | KCNH2DNM1 | |
| SCHEMBL15901718 | 0.91 | KCNH2 (0.45) | KCNH2DNM1 | |
| SCHEMBL27961113 | 0.91 | KCNH2 (0.45) | KCNH2DNM1 | |
| SCHEMBL15901281 | 0.91 | KCNH2 (0.45) | KCNH2DNM1 | |
| SCHEMBL22157415 | 0.91 | KCNH2 (0.45) | KCNH2DNM1 | |
| SCHEMBL15901895 | 0.91 | KCNH2 (0.45) | KCNH2DNM1 | |
| SCHEMBL6660072 | 0.91 | KCNH2 (0.50) | KCNH2PLA2G1BPLA2G2A | |
| SCHEMBL27961069 | 0.91 | KCNH2 (0.45) | KCNH2DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234553-A2 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |