SCHEMBL26258223

SCHEMBL26258223

C[C@H]1CC[C@@]2(CCO2)CC1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26258627 1.00 KDM4E (0.35) KDM4EPKM
SCHEMBL8384549 1.00 KDM4E (0.35) KDM4EPKM
SCHEMBL21285292 0.90 KDM4E (0.33) KDM4EPKM
SCHEMBL16659515 0.90 KDM4E (0.33) KDM4EPKM
SCHEMBL19455017 0.85 KCNH2 (0.34) KDM4EPKM
SCHEMBL18851523 0.85 KCNH2 (0.34) KDM4EPKM
SCHEMBL19455014 0.85 KCNH2 (0.34) KDM4EPKM
SCHEMBL14355438 0.80
SCHEMBL23570075 0.79 KDM4E (0.34) KDM4EPKM
SCHEMBL22759615 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023178181-A1 IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2023-09-21 WO disclosed
EP-4245756-A1 IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF Gilead Sciences, Inc. (US) 2023-09-20 EP disclosed