SCHEMBL26259604

SCHEMBL26259604

CCC1CCC(F)(P)CC1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19983269 0.91 KDM4E (0.35) KDM4EALDH1A1GAAHPGDSMN1; SMN2
SCHEMBL178339 0.79 KDM4E (0.42) KDM4EALDH1A1GAAHPGDSMN1; SMN2
SCHEMBL14137797 0.77 KDM4E (0.41) KDM4EALDH1A1GAAHPGDSMN1; SMN2
SCHEMBL19982905 0.77 KDM4E (0.41) KDM4EALDH1A1GAAHPGDSMN1; SMN2
SCHEMBL25792748 0.75 KDM4E (0.39) KDM4EALDH1A1GAAHPGDSMN1; SMN2
SCHEMBL22916595 0.74
SCHEMBL19381587 0.74
SCHEMBL19501864 0.73 KDM4E (0.45) KDM4EALDH1A1GAAHPGDSMN1; SMN2
SCHEMBL15014640 0.72 KDM4E (0.41) KDM4EALDH1A1GAAHPGDSMN1; SMN2
SCHEMBL21743224 0.72 KDM4E (0.41) KDM4EALDH1A1GAAHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4245756-A1 IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF Gilead Sciences, Inc. (US) 2023-09-20 EP disclosed
EP-4174056-A1 ARYL TETRAHYDROPYRIDINE DERIVATIVE OR SALT THEREOF, INSECTICIDE CONTAINING SAME, AND METHOD FOR USE THEREOF Nihon Nohyaku Co., Ltd. (JP) 2023-05-03 EP disclosed