Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 16/20 | 0.71 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26268355 | 0.98 | MAP3K14 (0.71) | MAP3K14MAPKAPK2PAK4ADORA2AADORA2B | |
| SCHEMBL26268320 | 0.83 | MAP3K14 (1.00) | MAP3K14MAPKAPK2 | |
| SCHEMBL30219597 | 0.83 | MAP3K14 (1.00) | MAP3K14MAPKAPK2 | |
| SCHEMBL26268315 | 0.82 | MAP3K14 (0.56) | MAP3K14PAK4ADORA2AADORA2BADORA1 | |
| SCHEMBL26270381 | 0.82 | MAP3K14 (0.51) | MAP3K14ADORA2AADORA2BADORA1 | |
| SCHEMBL30219583 | 0.81 | MAP3K14 (1.00) | MAP3K14MAPKAPK2 | |
| SCHEMBL28986323 | 0.81 | MAP3K14 (1.00) | MAP3K14MAPKAPK2 | |
| SCHEMBL26268435 | 0.81 | MAP3K14 (0.75) | MAP3K14 | |
| SCHEMBL26269507 | 0.81 | MAP3K14 (0.75) | MAP3K14 | |
| SCHEMBL26268328 | 0.81 | MAP3K14 (0.48) | MAP3K14PAK4ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177351-A1 | NF ҚB INDUCING KINASE INHIBITORS AND METHODS THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-09-21 | — | — | WO | disclosed |