SCHEMBL26272

SCHEMBL26272

C[CH]c1ncc(C)o1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17255099 0.82 TDP1 (0.30)
SCHEMBL17255100 0.82 TDP1 (0.30)
SCHEMBL12461697 0.81
SCHEMBL13282803 0.78
SCHEMBL12507909 0.72
SCHEMBL5154398 0.69
SCHEMBL15948607 0.68
SCHEMBL268792 0.67
SCHEMBL15070886 0.65
Ammonia Solution, Strong SCHEMBL27345029 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113874353-B Microbiocidal derivatives 先正达农作物保护股份公司 2024-06-14 CN disclosed
US-20230192628-A1 MICROBIOCIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-06-22 US disclosed
US-20220272976-A1 MICROBIOCIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2022-09-01 US disclosed
CN-113924294-A Microbicidal derivatives 先正达农作物保护股份公司 2022-01-11 CN disclosed
CN-113874353-A Microbicidal derivatives 先正达农作物保护股份公司 2021-12-31 CN disclosed
WO-2020239853-A1 MICROBIOCIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2020-12-03 WO disclosed
WO-2020239856-A1 MICROBIOCIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2020-12-03 WO disclosed
US-10336717-B2 Inhibitors of beta-secretase VITAE PHARMACEUTICALS, LLC (US) 2019-07-02 US disclosed
US-20160272600-A1 INHIBITORS OF BETA-SECRETASE VITAE PHARMACEUTICALS, LLC 2016-09-22 US disclosed
US-9212153-B2 Inhibitors of beta-secretase VITAE PHARMACEUTICALS, INC. (US) 2015-12-15 US disclosed
EP-2801570-A1 Inhibitors of beta-secretase Vitae Pharmaceuticals, Inc. (US) 2014-11-12 EP disclosed
US-20140200223-A1 INHIBITORS OF BETA-SECRETASE VITAE PHARMACEUTICALS, INC. 2014-07-17 US disclosed
US-8633212-B2 Inhibitors of beta-secretase VITAE PHARMACEUTICALS, INC. (US) 2014-01-21 US disclosed
EP-2406240-A2 INHIBITORS OF BETA-SECRETASE Vitae Pharmaceuticals, Inc. (US) 2012-01-18 EP disclosed
US-20110071126-A1 INHIBITORS OF BETA-SECRETASE VITAE PHARMACEUTICALS, INC. 2011-03-24 US disclosed
WO-2010105179-A2 INHIBITORS OF BETA-SECRETASE VITAE PHARMACEUTICALS, INC. (US) 2010-09-16 WO disclosed