SCHEMBL26276397

CC[C@H]1O[C@@H](n2cc(C)c(N)nc2=O)C[C@H]1OP(=O)(S)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C[C@H]1OP(=O)(S)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C[C@H]1OP(=O)(S)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C[C@H]1OP(=O)(S)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C[C@H]1OP(=O)(S)OC[C@H]1O[C@@H](n2cc(C)c(N)nc2=O)C[C@H]1OP(=O)(S)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C[C@H]1OP(=O)(S)OC

nearest known ligand 0.54

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	DTYMK	P23919	4/20	0.54

▸	TERT	O14746	2/20	0.48

▸	F2	P00734	2/20	0.44

▸	TK1	P04183	1/20	0.42

▸	POLB	P06746	1/20	0.41

▸	ENPP1	P22413	1/20	0.41

▸	P2RY1	P47900	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL27334184	1.00	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL25915846	1.00	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL27000503	1.00	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL27000423	1.00	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL18472073	1.00	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL17775306	1.00	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL26860042	1.00	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL18159196	1.00	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL27000635	1.00	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL20024801	1.00	DTYMK (0.54)	DTYMKTERTF2TK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240209364-A1	COMPOUNDS AND METHODS FOR MODULATING PLP1	IONIS PHARMACEUTICALS, INC. (US)	2024-06-27	—	—	US	disclosed
US-11732263-B2	Compounds and methods for modulating PLP1	IONIS PHARMACEUTICALS, INC. (US)	2023-08-22	—	—	US	disclosed