⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14788692 | 0.76 | — | — | |
| SCHEMBL16636734 | 0.73 | — | — | |
| SCHEMBL21720545 | 0.70 | — | — | |
| SCHEMBL21721492 | 0.70 | — | — | |
| SCHEMBL20439933 | 0.69 | — | — | |
| SCHEMBL20439914 | 0.68 | — | — | |
| SCHEMBL21720523 | 0.64 | KMT2A (0.32) | — | |
| SCHEMBL6873749 | 0.60 | — | — | |
| SCHEMBL19111706 | 0.60 | — | — | |
| SCHEMBL15178050 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | SIGNALRX PHARMACEUTICALS, INC. (US) | 2023-09-19 | — | — | US | disclosed |