Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 16/20 | 0.45 |
| ▸ | OXTR | P30559 | 3/20 | 0.45 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1495933 | 0.94 | AVPR1A (0.42) | AVPR1AOXTRIDH1DRD2 | |
| SCHEMBL1496069 | 0.87 | AVPR1A (0.42) | AVPR1AOXTRIDH1AVPR2 | |
| SCHEMBL1496096 | 0.86 | IDH1 (0.43) | AVPR1AOXTRIDH1AVPR2 | |
| SCHEMBL1496011 | 0.84 | AVPR1A (0.41) | AVPR1AOXTRAVPR2 | |
| SCHEMBL1495930 | 0.84 | AVPR1A (0.40) | AVPR1AOXTRIDH1AVPR2 | |
| SCHEMBL2629001 | 0.83 | IDH1 (0.37) | AVPR1AOXTRIDH1AVPR2 | |
| SCHEMBL1496129 | 0.83 | AVPR1A (0.43) | AVPR1AOXTRAVPR2 | |
| Hydrochloric Acid SCHEMBL1495896 | 0.83 | IDH1 (0.37) | AVPR1AOXTRIDH1AVPR2 | |
| SCHEMBL1496276 | 0.82 | AVPR1A (0.41) | AVPR1AOXTRAVPR2 | |
| SCHEMBL2628459 | 0.82 | IDH1 (0.40) | AVPR1AOXTRIDH1AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101082-A1 | VASOPRESSIN V1A ANTAGONISTS | BATT ANDRZEJ ROMAN (GB) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101082-A1 | VASOPRESSIN V1A ANTAGONISTS | AVPR1A, AVPR2, AVPR1B | AVPR1A 1/4885OXTR 8/4885IDH1 3133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.