Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 7/20 | 0.61 |
| ▸ | RET | P07949 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 11/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21521132 | 0.89 | PANK3 (0.57) | PANK3PARP1PARP2CHRM1 | |
| SCHEMBL19748497 | 0.87 | PANK3 (0.64) | PANK3PARP1PARP2CHRM1 | |
| SCHEMBL31464937 | 0.85 | PANK3 (0.57) | PANK3PARP1PARP2CHRM1 | |
| SCHEMBL30860008 | 0.85 | PANK3 (0.57) | PANK3PARP1PARP2CHRM1 | |
| SCHEMBL31464929 | 0.84 | PANK3 (0.61) | PANK3PARP1PARP2CHRM1 | |
| SCHEMBL15014105 | 0.84 | PANK3 (0.67) | PANK3PARP1PARP2CHRM1 | |
| SCHEMBL26292516 | 0.84 | PANK3 (0.61) | PANK3PARP1PARP2CHRM1 | |
| SCHEMBL26291098 | 0.84 | PANK3 (0.61) | PANK3PARP1PARP2CHRM1 | |
| SCHEMBL30859740 | 0.84 | PANK3 (0.61) | PANK3PARP1PARP2CHRM1 | |
| Hydrochloric Acid SCHEMBL21520720 | 0.83 | PANK3 (0.60) | PANK3PARP1PARP2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234551-A2 | PYRIDAZINONES AS PARP7 INHIBITORS | Ribon Therapeutics Inc. (US) | 2023-08-30 | — | — | EP | disclosed |