Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 13/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 13/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 1.00 |
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | POLB | P06746 | 10/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 8/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 1.00 |
| ▸ | BLM | P54132 | 6/20 | 1.00 |
| ▸ | APEX1 | P27695 | 4/20 | 1.00 |
| ▸ | PTGES | O14684 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 6/20 | 0.66 |
| ▸ | PKM | P14618 | 6/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26295896 | 0.86 | MCL1 (0.82) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL24277667 | 0.86 | MCL1 (1.00) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL24277194 | 0.85 | MCL1 (0.80) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL24277665 | 0.85 | MCL1 (0.80) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL26294556 | 0.85 | MEN1 (0.73) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL24277568 | 0.84 | MEN1 (0.73) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL24277912 | 0.83 | MEN1 (0.74) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL26293205 | 0.83 | MEN1 (0.69) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL24277916 | 0.82 | MCL1 (0.74) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL26761824 | 0.81 | MEN1 (0.68) | MEN1KMT2AALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168240-A1 | SMALL MOLECULE INHIBITORS OF ENPP1 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-09-07 | — | — | WO | disclosed |