Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 16/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 14/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22132788 | 1.00 | FGFR1 (0.47) | FGFR1FGFR4FGFR3FGFR2KDR | |
| SCHEMBL22132924 | 0.92 | FGFR1 (0.54) | FGFR1FGFR4FGFR3FGFR2KDR | |
| SCHEMBL22186335 | 0.92 | FGFR1 (0.54) | FGFR1FGFR4FGFR3FGFR2KDR | |
| SCHEMBL22132841 | 0.92 | FGFR1 (0.54) | FGFR1FGFR4FGFR3FGFR2KDR | |
| SCHEMBL22132921 | 0.85 | FGFR1 (0.63) | FGFR1FGFR4FGFR3FGFR2KDR | |
| SCHEMBL22132909 | 0.85 | FGFR1 (0.63) | FGFR1FGFR4FGFR3FGFR2KDR | |
| SCHEMBL22132910 | 0.85 | FGFR1 (0.63) | FGFR1FGFR4FGFR3FGFR2KDR | |
| SCHEMBL22132877 | 0.83 | FGFR4 (0.61) | FGFR1FGFR4FGFR3FGFR2KDR | |
| SCHEMBL22132850 | 0.83 | FGFR4 (0.61) | FGFR1FGFR4FGFR3FGFR2KDR | |
| SCHEMBL22132878 | 0.83 | FGFR4 (0.61) | FGFR1FGFR4FGFR3FGFR2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3670513-B1 | FGFR INHIBITOR AND MEDICAL APPLICATION THEREOF | CSPC ZHONGQI PHARMACEUTICAL TECH SHIJIAZHUANG CO LTD (CN) | 2023-09-20 | — | — | EP | disclosed |