Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 2/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25406413 | 0.91 | ATR (0.41) | ATRMAP3K7MTORPIK3CA | |
| SCHEMBL25405929 | 0.91 | ATR (0.41) | ATRMAP3K7MTORPIK3CA | |
| SCHEMBL26301096 | 0.84 | ATR (0.37) | ATRMAP3K7 | |
| SCHEMBL25407695 | 0.80 | ATR (0.49) | ATR | |
| SCHEMBL25408256 | 0.80 | ATR (0.49) | ATR | |
| SCHEMBL26289452 | 0.72 | ATR (0.44) | ATRMTORPIK3CA | |
| SCHEMBL25405924 | 0.72 | ATR (0.44) | ATRMTORPIK3CA | |
| SCHEMBL25410054 | 0.71 | ATR (0.43) | ATRMAP3K7MTORPIK3CA | |
| SCHEMBL25405358 | 0.71 | ATR (0.43) | ATRMAP3K7MTORPIK3CA | |
| SCHEMBL26290771 | 0.71 | ATR (0.44) | ATRMAP3K7MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295166-A1 | ATR INHIBITORS AND USES THEREOF | ANTENGENE DISCOVERY LIMITED (CN) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295166-A1 | ATR INHIBITORS AND USES THEREOF | ATR, CHEK1, CHEK2 | ATR 1/4885MAP3K7 279/4885MTOR 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.