SCHEMBL26301845

SCHEMBL26301845

Nc1ccc(-c2cc(C(=O)c3ccccc3)n3ccccc23)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 6/20 0.61
▸ FNTB P49356 6/20 0.61
▸ BAZ2B Q9UIF8 7/20 0.51
▸ BAZ2A Q9UIF9 7/20 0.51
▸ TUBB4A P04350 1/20 0.43
▸ TUBB P07437 1/20 0.43
▸ TUBA3C P0DPH7 1/20 0.43
▸ TUBA1B P68363 1/20 0.43
▸ TUBA4A P68366 1/20 0.43
▸ TUBB4B P68371 1/20 0.43
▸ TUBB3 Q13509 1/20 0.43
▸ TUBB2A Q13885 1/20 0.43
▸ TUBB8 Q3ZCM7 1/20 0.43
▸ TUBA3E Q6PEY2 1/20 0.43
▸ TUBA1A Q71U36 1/20 0.43
▸ TUBA1C Q9BQE3 1/20 0.43
▸ TUBB6 Q9BUF5 1/20 0.43
▸ TUBB2B Q9BVA1 1/20 0.43
▸ TUBB1 Q9H4B7 1/20 0.43
▸ PBRM1 Q86U86 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26301414 0.90 FNTA (0.69) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL26301880 0.87 FNTA (0.67) FNTAFNTBBAZ2BBAZ2A
SCHEMBL26301387 0.84 FNTA (0.59) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL26301735 0.84 BAZ2B (0.46) FNTAFNTBBAZ2BBAZ2ATUBB4A
SCHEMBL26301819 0.83 FNTA (0.61) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL26301829 0.83 FNTA (0.54) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL26301430 0.82 FNTA (0.57) FNTAFNTBBAZ2BBAZ2ATUBB4A
SCHEMBL26301438 0.82 BAZ2B (0.74) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL26301363 0.82 FNTA (0.57) FNTAFNTBBAZ2BBAZ2A
SCHEMBL26301866 0.79 BAZ2B (0.55) FNTAFNTBBAZ2BBAZ2ABRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
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