SCHEMBL26306535

SCHEMBL26306535

COc1ccc(-c2noc(N3CCC(C(=O)NCC4CCN(C(=O)OC(C)(C)C)C4)CC3)n2)cc1

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.61
▸ MEN1 O00255 4/20 0.58
▸ KMT2A Q03164 4/20 0.58
▸ LMNA P02545 3/20 0.57
▸ MAPT P10636 3/20 0.54
▸ NPC1 O15118 1/20 0.53
▸ HTT P42858 1/20 0.53
▸ POLB P06746 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30584814 1.00 SMN1; SMN2 (0.61) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL30585037 1.00 SMN1; SMN2 (0.61) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL30584978 0.91 MEN1 (0.54) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL30584852 0.91 MEN1 (0.54) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL30584913 0.91 MEN1 (0.54) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL30584709 0.91 MEN1 (0.54) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL30584961 0.91 MEN1 (0.54) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL26306603 0.91 MAPT (0.56) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL25438967 0.91 SMN1; SMN2 (0.49) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL30584737 0.91 SMN1; SMN2 (0.49) SMN1; SMN2MEN1KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 SMN1; SMN2 3115/4885MEN1 1569/4885KMT2A 1404/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 SMN1; SMN2 3115/4885MEN1 1569/4885KMT2A 1404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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