SCHEMBL26306937

SCHEMBL26306937

CN1CCC(CNC(=O)C2CCN(c3nc(-c4ccc(Cl)cc4)no3)CC2)C1

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.54
▸ LMNA P02545 2/20 0.54
▸ MEN1 O00255 4/20 0.53
▸ KMT2A Q03164 4/20 0.53
▸ POLB P06746 1/20 0.48
▸ HDAC4 P56524 1/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25435289 0.90 MEN1 (0.48) MAPTLMNAMEN1KMT2APOLB
SCHEMBL25436110 0.90 MEN1 (0.48) MAPTLMNAMEN1KMT2APOLB
SCHEMBL31546363 0.90 MEN1 (0.48) MAPTLMNAMEN1KMT2APOLB
SCHEMBL25402463 0.90 MEN1 (0.48) MAPTLMNAMEN1KMT2APOLB
SCHEMBL25435085 0.90 MEN1 (0.48) MAPTLMNAMEN1KMT2APOLB
SCHEMBL25402468 0.90 MEN1 (0.48) MAPTLMNAMEN1KMT2APOLB
SCHEMBL25439279 0.89 MAPT (0.52) MAPTLMNAMEN1KMT2APOLB
SCHEMBL25439629 0.89 MAPT (0.52) MAPTLMNAMEN1KMT2APOLB
SCHEMBL25433029 0.89 MEN1 (0.67) MAPTLMNAMEN1KMT2APOLB
SCHEMBL25439278 0.89 MAPT (0.52) MAPTLMNAMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed
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