Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 15/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26308566 | 1.00 | CYP1A2 (0.43) | CYP1A2SCN5AMETCYP3A4PDE1A | |
| SCHEMBL22745008 | 0.93 | CYP1A2 (0.51) | CYP1A2SCN5AMET | |
| SCHEMBL22744830 | 0.93 | CYP1A2 (0.51) | CYP1A2SCN5AMET | |
| SCHEMBL22745009 | 0.93 | CYP1A2 (0.51) | CYP1A2SCN5AMET | |
| SCHEMBL26539659 | 0.89 | CYP1A2 (0.43) | CYP1A2SCN5AMETPDE1APDE4C | |
| SCHEMBL26539658 | 0.89 | CYP1A2 (0.43) | CYP1A2SCN5AMETPDE1APDE4C | |
| SCHEMBL26539661 | 0.89 | CYP1A2 (0.43) | CYP1A2SCN5AMETPDE1APDE4C | |
| SCHEMBL26308517 | 0.82 | CYP1A2 (0.45) | CYP1A2SCN5AMET | |
| SCHEMBL26539275 | 0.82 | CYP1A2 (0.58) | CYP1A2SCN5AMETCYP3A4 | |
| SCHEMBL23522697 | 0.82 | CYP1A2 (0.52) | CYP1A2SCN5AMETPDE1APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286984-A1 | ION CHANNEL MODULATORS | PRAXIS PRECISION MEDICINES, INC. | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286984-A1 | ION CHANNEL MODULATORS | SCN1A, SCN1B, SCN2A | CYP1A2 2437/4885SCN5A 5/4885MET 4804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.