Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23843049 | 0.94 | KLKB1 (0.42) | KLKB1RBP4 | |
| SCHEMBL23843044 | 0.91 | KLKB1 (0.38) | KLKB1 | |
| SCHEMBL26307682 | 0.89 | KLKB1 (0.55) | KLKB1RBP4 | |
| SCHEMBL26310197 | 0.86 | KLKB1 (0.46) | KLKB1 | |
| SCHEMBL23843048 | 0.83 | KLKB1 (0.54) | KLKB1RBP4 | |
| SCHEMBL23843140 | 0.82 | KLKB1 (0.44) | KLKB1 | |
| SCHEMBL23843119 | 0.80 | KLKB1 (0.40) | KLKB1 | |
| SCHEMBL23843045 | 0.80 | KLKB1 (0.49) | KLKB1 | |
| SCHEMBL23843112 | 0.80 | KLKB1 (0.45) | KLKB1 | |
| SCHEMBL23843040 | 0.79 | KLKB1 (0.38) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760745-B2 | Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760745-B2 | Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors | KLKB1, KLK5, KLK1 | KLKB1 1/4885RBP4 3590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.